Efficacy of Intra-articular Steroid

Intra-articular steroid therapy in rheumatoid arthritis.

The introduction of steroid preparations into joint cavities has become a routine method of treating some cases of rheumatoid arthritis. Murdoch and Will (1959a, b) have drawn attention to the persistence of prednisolone trimethyl acetate (P.T.M.A.) in the joint cavity and to its, apparently, purely local effect when administered in this way. Since then, Triamcinolone (T.C.A.), Dexamethasone (D...

Safety and Efficacy of Single Intra-Articular

Objectives: To assess, in daily practice conditions, both safety and efficacy of a single intra-articular injection of a cross-linked hyaluronic acid (HA) combined with mannitol (HANOX-M-XL) in patients with symptomatic knee osteoarthritis. Methods: We analyzed the clinical and radiological data of 53 consecutive patients with symptomatic knee OA, treated between January and June 2016 with a si...

Efficacy of Intra-articular Steroid Injection in Patients with Femoroacetabular Impingement

Femoroacetabular Impingement (FAI) arises from morphological abnormalities between the proximal femur and acetabulum. Impingement caused by these morphologic abnormalities induces early degenerative changes in the hip joint. Furthermore, FAI patients complain of severe pain and limited range of motion in the hip, but a guideline for treatment of FAI has not yet been established. Medication, sup...

Importance of placement of intra-articular steroid injections.

Release of lubricating synovial surfactant by intra-articular steroid.

This study was undertaken to determine whether glucocorticosteroids promote the secretion of lubricating surfactant, i.e. surface-active phospholipid (SAPL), into the joint. A standard clinical dose (100 mg) of methylprednisolone acetate (MPA) in 2.5 ml of saline was injected into the load-bearing right radiocarpal joint of five horses and 2.5 ml of saline injected into each of the contralatera...